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1 article(s) from Herziger, Svenja

Supramolecular polymerization of sulfated dendritic peptide amphiphiles into multivalent L-selectin binders

David Straßburger,
Svenja Herziger,
Katharina Huth,
Moritz Urschbach,
Rainer Haag and
Pol Besenius

Beilstein J. Org. Chem. 2021, 17, 97–104, doi:10.3762/bjoc.17.10

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Scheme 1: The synthesis of the C₃-symmetrical tetraethylene glycol-decorated peptide amphiphile I and the azi...

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Scheme 2: Synthesis of the sulfated peptide amphiphile II by copper-catalyzed azide–alkyne cyclization.

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Figure 1: Analysis of the self-assembly behavior of I by A: CD-spectra of 5, 10, 25 or 50 µM aqueous solution...

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Figure 2: Analysis of the supramolecular polymerization of II by A: CD-spectra of a 25 µM solution in TRIS bu...

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Figure 3: Concentration-dependent relative L-selectin binding of the supramolecular polymers I and II in HEPE...

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Published 12 Jan 2021

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